Bone Image Analysis Workshop

Join us for a presentation and discussion on how to achieve quantitative image analysis and interpretation of your 3D/4D bone research images with Dragonfly.

October 1, 2018 in Montreal, Canada

 

You are invited to a free bone image analysis workshop in Montreal, Canada!

Join us for a presentation and discussion on how to achieve quantitative image analysis and interpretation of your 3D/4D bone research images with Dragonfly. Learn how to create informative and stunning animations, while extracting out microstructural details with innovative tools that span multiple length scales. The image segmentation capabilities of Dragonfly will drastically improve your imaging research productivity.

Please share this invitation with your colleagues who will be in Montreal for ASBMR!

Monday, October 1, 2018 from 15:30 to 19:30
Meeting Room HIbiscus A&B
Holiday Inn, 999 St-Urbain (next to the Palais des congrès de Montréal)
Montreal, Quebec, Canada H2Z 0B4 (Get Directions)

Register to Attend

NOTE Space is limited. Register now to reserve your spot.


AGENDA

The multidimensional landscape of bone structure-function relations
Presented by Natalie Reznikov, PhD
Faculty of Dentistry, McGill University

3D visualization, segmentation, and morphological assessment of osteocyte lacunae using nano-computed tomography
Presented by Jennifer Coulombe & Virginia Ferguson, PhD
Materials Science and Engineering, University of Colorado at Boulder

New features for bone analysis in Dragonfly
Presented by Mike Marsh, PhD
Dragonfly Product Manager, ORS


BONE ANALYSIS FOR DRAGONFLY 4.0

The Bone Analysis module for Dragonfly 4.0 is a powerful pre-clinical research application designed for the evaluation of 3D microCT image data. This module can generate an extensive set of bone morphometric indices from segmented whole bone specimens and from isolated 3D samples of cortical and trabecular bone tissue.

Starting from automatic and user-guided isolation of bone from non-bone tissue by means of threshold-based segmentation, the Bone Analysis module can then separately identify cortical and trabecular bone in whole-bone specimens. The calculation of common bone morphometric indices from these segmented regions then provides researchers with quantitative descriptions of bone microarchitecture. The available measurements for segmented trabecular and cortical bone are listed in the tables below.

Global measurements for segmented cortical and trabecular areas

Indice Abbreviation Measurement
Anisotropy (from MIL) -- --
Anisotropy (from SVD) -- --
Bone Volume BV (default unit)3
Total Volume TV (default unit)3
Bone Volume Fraction BV/TV %
Average Cortical Thickness Ct.Th default unit
Average Trabecular Thickness Tb.Th default unit
Average Trabecular Separation Tb.Sp default unit
Average Cortical Area Ct.Ar (default unit)2
Average Marrow Area Ma.Ar (default unit)2
Average Total (Cortical + Marrow) Area Tt.Ar (default unit)2
Average Cortical Area Fraction Ct.Ar/Tt.Ar %
Periosteal Surface (3D Evaluation) Ps.S3D (default unit)2
Endocortical Surface (3D Evaluation) Ec.S3D (default unit)2
Average Periosteal Perimeter Ps.Pm default unit
Average Endocortical Perimeter Ec.Pm default unit

Per slice (any oblique) measurements for segmented cortical and trabecular areas

Indice Abbreviation Measurement
Moment of Inertia Anteroposterior Axis Iap (default unit)4
Moment of Inertia Mediolateral Axis Iml (default unit)4
Maximum Moment of Inertia Imax (default unit)4
Minimum Moment of Inertia Imin (default unit)4
Polar Moment of Inertia J (default unit)4
Average Cortical Thickness Ct.Th default unit
Average Trabecular Thickness Tb.Th default unit
Average Trabecular Separation Tb.Sp default unit
Periosteal Perimeter Ps.Pm default unit
Endocortical Perimeter Ec.Pm default unit

In adition to the above indices, the Bone Analysis module provides mapping of anisotropy as follows:

  • Map of local anisotropy
  • Field of local anisotropy orientation

Bone Analysis results…

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